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You take Accutane by mouth every day for several months, then stop. You must have two negative pregnancy tests before beginning Accutane therapy, and must take monthly pregnancy tests while using this drug. In addition, you must use 2 forms of birth control during Accutane therapy, and for 1 month before and after. Each prescription for Accutane must bear a yellow qualification sticker signifying that you meet these requirements. Concomitant treatment with tetracyclines should therefore be avoided.
WarningsImpaired hearing has been reported in patients taking Accutane; in some cases, the hearing impairment has been reported to persist after therapy has been discontinued. Mechanism(s) and causality for this event have not been established. Clinical hepatitis considered to be possibly or probably related to Accutane therapy has been reported. Accutane has been associated with inflammatory bowel disease (including regional ileitis) in patients without a prior history of intestinal disorders. Special Warnings About Accutaneyou are a woman of childbearing age and you are considering taking Accutane, you will be given both spoken and written warnings (the iPLEDGE program) about the importance of avoiding pregnancy during the treatment. You will also be asked to sign a second consent form noting that:You must not take Accutane if you are pregnant, may become pregnant during treatment, or are breastfeeding;If you get pregnant while taking Accutane, your baby will be at high risk for birth defects;If you take Accutane, you must use 2 effective forms of birth control from 1 month before the start of treatment through 1 month after the end of treatment;You must have 2 negative pregnancy tests (one just before starting Accutane therapy), and must be tested every month during therapy;You may participate in a program that includes an initial free pregnancy test and birth control counseling session;If you become pregnant, you must immediately stop taking Accutane and see your doctor;You have read and understood the Accutane patient brochure and asked your doctor any questions you had;You have been invited to participate in a survey of women being treated with Accutane.Some people taking Accutane, including some who simultaneously took tetracycline, have experienced headache, nausea, and visual disturbances caused by increased pressure within the skull. OverdosageAny medication taken in excess can have serious consequences. If you suspect an overdose of Accutane, seek medical attention immediately. This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. |
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