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cardiovascular / Generic Aggrenox OrderMedications.org gives you the chance to buy aggrenox tablets and quality Cardiovascular drugs at discount prices from the privacy of your home.
Aggrenox should be taken once in the morning and once in the evening. The capsule should be swallowed whole without chewing. This drug may be taken with or without food.If you miss a dose...Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. You should not take Aggrenox if you have ever had an allergic reaction to aspirin, dipyridamole, or nonsteroidal anti-inflammatory drugs.
Where Should I Keep This Medicine?If you are experiencing these side effects you can continue your treatment but please inform your physician at once. Follow the directions on the label. The capsules must be swallowed whole. Do not crush or chew. You can take this medicine with or without food. Take your doses at regular intervals. Also tell them if you smoke, drink alcohol, or use illegal drugs. The following information was obtained from the literature. Adenosine: Dipyridamole has been reported to increase the plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary. Angiotensin Converting Enzyme (ACE), Inhibitors: Due to the indirect effect of aspirin on the renin-angiotensin conversion pathway, the hyponatremic and hypotensive effects of ACE inhibitors may be diminished by concomitant administration of aspirin. Recommended Dosage For AggrenoxInform you doctor if you are taking any additional medicines of this kind during your treatment with Aggrenox. He might lower your Aggrenox dosage or monitor the way your body reacts to the treatment. Do not take your medicine more often than directed.Talk Anticoagulant Therapy (heparin and warfarin): Patients on anticoagulation therapy are at increased risk for bleeding because of drug-drug interactions and effects on platelets. Aspirin can displace warfarin from protein binding sites, leading to prolongation of both the prothrombin time and the bleeding time. What If I Miss A Dose?In ESPS2 the incidence of gastrointestinal bleeding was 68 patients (4.1%) in the Aggrenox group, 36 patients (2.2%) in the extended-release dipyridamole group, 52 patients (3.2%) in the aspirin group, and 34 patients (2.1%) in the placebo groups. medicine may also interact with the following:acetazolamide , adenosine , antiinflammatory drugs, NSAIDs like ibuprofen , aspirin-containing medicines or other salicylates , diuretics , medicines for Alzheimer's disease or myasthenia gravis , medicines for diabetes that are taken by mouth , medicines for high blood pressure like ACE inhibitors or beta-blockers , medicines for seizures like phenytoin or valproic acid , probenecid , sulfinpyrazone.This list may not describe all possible interactions. PrecautionsDo not take other aspirin products unless directed by your doctor or health care professional. Patients with high frequency hearing loss may have difficulty perceiving tinnitus. In these patients, tinnitus cannot be used as a clinical indicator of salicylism Heart Rate and Rhythm Disorders: Tachycardia, palpitation, arrhythmia, supraventricular tachycardia Liver and Biliary System Disorders: Cholelithiasis, jaundice, hepatic function abnormal Metabolic and Nutritional Disorders: Hyperglycemia, thirst Platelet, Bleeding and Clotting Disorders: Hematoma, gingival bleeding Psychiatric Disorders: Agitation Reproductive: Uterine hemorrhage Respiratory: Hyperpnea, asthma, bronchospasm, hemoptysis, pulmonary edema Special Senses Other Disorders: Taste loss Skin and Appendages Disorders: Pruritus, urticaria Urogenital: Renal insufficiency and failure, hematuria Vascular (Extracardiac) Disorders: Flushing The following is a list of additional adverse reactions that have been reported either in the literature or are from postmarketing spontaneous reports for either dipyridamole or aspirin. Adverse ReactionsMany non-prescription medicines contain aspirin. To prevent accidental overdose, read labels carefully and do not take more than one product that contains aspirin.If you have diabetes, this medicine may affect your blood sugar levels. In case of real or suspected overdose, seek medical attention or contact a Poison Control Center immediately. Symptomatic treatment is recommended, possibly including a vasopressor drug. Gastric lavage should be considered. A 24-month, multicenter, double-blind, randomized study (ESPS2) was conducted to compare the efficacy and safety of Aggrenox capsules with placebo, extended-release dipyridamole alone and aspirin alone. OverdosageBased upon the known hemodynamic effects of dipyridamole, symptoms such as warm feeling, flushes, sweating, restlessness, feeling of weakness and dizziness may occur. Aspirin is contraindicated in patients with known allergy to nonsteroidal anti-inflammatory drug products and in patients with the syndrome of asthma, rhinitis, and nasal polyps. A drop in blood pressure and tachycardia might also be observed. Administration of xanthine derivatives (e.g., aminophylline) may reverse the hemodynamic effects of dipyridamole overdose. |
