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You are allergic to any ingredient in Glimepiride, you have type 1 diabetes, severe second or third degree burns, increased ketone levels, severely increased acid levels in your bodily fluids (acidosis), or a history of a diabetic coma, you are pregnant and near delivery, you are using bosentan or drink alcohol. Patients who are 65 years of age or older may experience a stronger physical reaction to this product so it is advised to lower their dosage. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Amaryl.Side effects may include:Anemia and other blood disorders, blurred vision, diarrhea, dizziness, headache, itching, liver problems and jaundice, muscle weakness, nausea, sensitivity to light, skin rash and eruptions, stomach and intestinal pain, vomitingAmaryl, like all oral antidiabetics, can result in hypoglycemia (low blood sugar).
Glimepiride Is Used For:If you have any of the following cases, you might not be allowed to take Amaryl or you might need a dosage adjustment or special monitoring during the treatment. Failure to follow an appropriate dosage regimen may precipitate hypoglycemia. Do not drink alcohol while you are using Glimepiride. It can increase the risk of developing abnormally low blood sugar. Alcohol can sometimes interact with Glimepiride and cause a serious reaction with symptoms such as facial flushing, nausea, vomiting, dizziness, or stomach pain. Glimepiride Additional InformationGlycosylated hemoglobin levels should be performed to monitor the patients response to therapy. Take Amaryl exactly as you doctor tells you to. If your blood sugar level is often higher than it should be and you are taking Glimepiride according to directions, check with your doctor. Glimepiride may cause low blood sugar (eg, increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, or fainting). It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you do not have a reliable source of glucose available, eat a quick source of sugar, such as table sugar, honey, or candy, or drink a glass of orange juice or nondiet soda to quickly raise your blood sugar level. Amaryl Drug ReactionsIf necessary, your doctor will gradually increase the dose 1 or 2 milligrams at a time every 1 or 2 weeks. Your diabetes will probably be controlled on 1 to 4 milligrams a day; the most you should take in a day is 8 milligrams. If the maximum dose fails to do the job, your doctor may add Glucophage to your regimen. Weakened or malnourished people and those with adrenal, pituitary, kidney, or liver disorders are particularly sensitive to hypoglycemic drugs such as Amaryl and should start at 1 milligram once daily. Amaryl OverdoseIf overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Significant concentrations of glimepiride were observed in the serum and breast milk of the dams as well as in the serum of the pups. These skeletal deformations were determined to be the result of nursing from mothers exposed to glimepiride. In rat reproduction studies, significant concentrations of glimepiride were observed in the serum and breast milk of the dams, as well as in the serum of the pups. OverdosageMild hypoglycemic symptoms without loss of consciousness or neurologic findings should be treated aggressively with oral glucose and adjustments in drug dosage and/or meal patterns. Close monitoring should continue until the physician is assured that the patient is out of danger. Severe hypoglycemic reactions with coma, seizure, or other neurological impairment occur infrequently, but constitute medical emergencies requiring immediate hospitalization. If hypoglycemic coma is diagnosed or suspected, the patient should be given a rapid intravenous injection of concentrated (50%) glucose solution. Overdosage of sulfonylureas, including Amaryl, can produce hypoglycemia. |
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