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Amoxapine is used to treat depression. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. They need to know if you have any of these conditions:difficulty passing urine , glaucoma , heart disease or recent heart attack , kidney disease , liver disease , Parkinson's disease , seizures , suicidal thoughts or family history of suicide , an unusual or allergic reaction to amoxapine, other medicines, foods, dyes, or preservatives , pregnant or trying to get pregnant , breast-feeding.
Dosage and using AmoxapineAmoxapine comes as a tablet to be taken orally. It is usually taken one or more times a day and may be taken with or without food. Take each dose with a full glass (8 oz) of water. It may take up to 4 weeks or more before you start feeling improvements, but do not stop taking this medicine without first talking to your doctor. Adverse EffectsAlthough some of the adverse reactions included in the following list have not been reported with amoxapine, pharmacological similarities among the tricyclic antidepressants require that each of the reactions be considered when prescribing amoxapine. With amoxapine, as with other tricyclic antidepressant drugs, the side effects most often reported are sedation and anticholinergic effects. Extrapyramidal symptoms reported with amoxapine include: akinesia, akathisia, chorea, cogwheel rigidity, dysarthria, mask-like facies, oculogyric crisis, torticollis and dyskinesia, including tardive dyskinesia. Although most of these symptoms have been reported infrequently, the possibility of their occurrence should be borne in mind when prescribing amoxapine. Amoxapine TreatmentTreatment should be symptomatic and supportive, but with special attention to prevention or control of seizures. External stimulation should be minimized to reduce the tendency to convulsions. ECG monitoring in an intensive care unit is recommended in all patients with tricyclic antidepressant overdosage, although cardiac complications do not appear to be as serious a problem with amoxapine overdosage as with some other tricyclic antidepressants, and the ECG typically remains within normal limits except for sinus tachycardia. In children, the initial dosage should not exceed 0.5 mg and should be adjusted to age and response. |
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