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Generic Casodex Bicalutamide 50mg

Check the label on the medicine for exact dosing instructions. Bicalutamide may be taken with or without food. Take Bicalutamide with your other prostate cancer medicine at the same time each day. If you miss a dose of Bicalutamide , take it as soon as possible. Bicalutamide may cause constipation or diarrhea. If you experience either constipation or diarrhea, ask your doctor or pharmacist to recommend a treatment for you. LAB TESTS, including liver function tests and prostate-specific antigen (PSA), may be required to monitor your progress. Be sure to keep all doctor and lab appointments. Use Bicalutamide with caution in the ELDERLY because they may be more sensitive to its effects.

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Precautions

Do not take more of Casodex than prescribed by your doctor. If a dose is missed, however, take it as soon as remembered. Casodex reacts with Warfarin, a blood thinner. Taking Casodex with Warfarin may cause bleeding. You may need monitoring in your Casodex or Warfarin therapy. There is no evidence of Leydig cell hyperplasia in patients; uterine tumors are not relevant to the indicated patient population. A small increase in the incidence of hepatocellular carcinoma in male mice given 75 mg/kg/day of bicalutamide (approximately 4 times human therapeutic concentrations*) and an increased incidence of benign thyroid follicular cell adenomas in rats given 5 mg/kg/day (approximately 2/3 human therapeutic concentrations*) and above were recorded.

Casodex Side Effects

If you experience any of these, discontinue taking Casodex and inform your doctor immediately. Casodex also has less serious side effects that are more likely to occur. Casodex is not indicated for use in women. It is not known whether this drug is excreted in human milk. In patients with advanced prostate cancer treated with Casodex in combination with an LHRH analogue, the most frequent adverse experience was hot flashes (53%). Administration of Casodex may lead to inhibition of spermatogenesis.

Casodex Drug Reactions

These neoplastic changes were progressions of non-neoplastic changes related to hepatic enzyme induction observed in animal toxicity studies. Enzyme induction has not been observed following bicalutamide administration in man. Long-term clinical trials have been conducted with dosages up to 200 mg of Casodex daily and these dosages have been well tolerated. A single dose of Casodex that results in symptoms of an overdose considered to be life-threatening has not been established. There is no specific antidote; treatment of an overdose should be symptomatic. In the management of an overdose with Casodex, vomiting may be induced if the patient is alert. It should be remembered that, in this patient population, multiple drugs may have been taken.