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In more serious infections, such as middle ear infection, the usual dose is 40 milligrams per 2.2 pounds of body weight per day divided into smaller doses. Average levels were 0.18, 0.20, 0.21, and 0.16 mg/mL at 2, 3, 4, and 5 hours respectively. Trace amounts were detected at 1 hour. The effect on nursing infants is not known. Transitory abnormalities in clinical laboratory test results have been reported.
Ceclor OverdosageSymptoms of Ceclor overdose may include: Diarrhea, nausea, stomach upset, vomiting If other symptoms are present, they may be related to an allergic reaction or other underlying disease. Small amounts of Ceclor have been detected in mother's milk following administration of single 500-mg doses. Although they were of uncertain etiology, they are listed below to serve as alerting information for the physician. In addition to the adverse reactions listed above that have been observed in patients treated with cefaclor, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics: fever, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, hemorrhage, false positive test for urinary glucose, elevated bilirubin, elevated LDH, and pancytopenia. Cefaclor Drug informationCeclor drug label information in our database does not contain a dedicated section on drug interactions. Meticulously monitor and maintain, within acceptable limits, the patient's vital signs, blood gases, serum electrolytes, etc. Absorption of drugs from the gastrointestinal tract may be decreased by giving activated charcoal, which, in many cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric emptying. Repeated doses of charcoal over time may hasten elimination of some drugs that have been absorbed. Cefaclor ToxicityThe toxic symptoms of cefaclor may include nausea, vomiting, epigastric distress, and diarrhea. The severity of the epigastric distress and the diarrhea are dose related. If other symptoms are present, it is probable that they are secondary to an underlying disease state, an allergic reaction, or the effects of other intoxication. Treatment "To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. Telephone numbers of certified poison control centers are listed in the Physicians' Desk Reference (PDR). Possibility Of Drug OverdosageIn managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient. Unless 5 times the normal dose of cefaclor has been ingested, gastrointestinal decontamination will not be necessary. Protect the patient's airway and support ventilation and perfusion. Safeguard the patient's airway when employing gastric emptying or charcoal. |
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