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You are allergic to any ingredient in Citalopram, you are taking or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) or St. John's wort within the last 14 days, you are taking astemizole, pimozide, dexfenfluramine, fenfluramine, phenothiazines (eg, thioridazine), sibutramine, or terfenadine. If Celexa gives you an allergic reaction, you cannot continue using it. The effects of Celexa during pregnancy have not been adequately studied, and the potential for harm has not been ruled out.
Dosage And AdministrationNever take double doses of Celexa unless otherwise prescribed by your doctor. If you happen to miss a dose and it is yet a long time for the next scheduled dose, you may take your missed dose. Psychiatric/medical check-ups and possibly lab tests should be done periodically to monitor your progress or check for side effects. In studies in normal volunteers, Celexa in doses of 40 mg/day did not produce impairment of intellectual function or psychomotor performance. Caution is advisable in using Celexa in patients with diseases or conditions that produce altered metabolism or hemodynamic responses. Celexa WarningHowever, the electrocardiograms of 1116 patients who received Celexa in clinical trials were evaluated and the data indicate that Celexa is not associated with the development of clinically significant ECG abnormalities. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Taking certain medications with this product could result in serious (rarely fatal) drug interactions. Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) with citalopram for 2 weeks before treatment, during treatment, or for 2 weeks after your last dose of citalopram. Adverse ReactionsIn particular, some evidence suggests that SSRIs can cause such untoward sexual experiences. Reliable estimates of the incidence and severity of untoward experiences involving sexual desire, performance, and satisfaction are difficult to obtain, however, in part because patients and physicians may be reluctant to discuss them. Celexa and placebo groups were compared with respect to (1) mean change from baseline in vital signs (pulse, systolic blood pressure, and diastolic blood pressure) and (2) the incidence of patients meeting criteria for potentially clinically significant changes from baseline in these variables. Management Of OverdoseIt is estimated that over 30 million patients have been treated with Celexa since market introduction. Establish and maintain an airway to ensure adequate ventilation and oxygenation. Gastric evacuation by lavage and use of activated charcoal should be considered. Careful observation and cardiac and vital sign monitoring are recommended, along with general symptomatic and supportive care. Due to the large volume of distribution of citalopram, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit. There are no specific antidotes for Celexa. In managing overdosage, consider the possibility of multiple-drug involvement. |
