anti depressants / Generic Effexor

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Generic Effexor

Generic Effexor

Venlafaxine 37.5/75mg

It may also be used for other conditions as determined by your doctor. Venlafaxine is a serotonin and norepinephrine reuptake inhibitor (SNRI). Effexor XR once at the same time each day. Swallow the capsule whole with water. Do not divide, crush, or chew it. Side effects cannot be anticipated. If you experience a major depressive episode, there's a slight chance that it could be the first signs of bipolar disorder. Tell your doctor about all your symptoms, and note that Effexor is not approved for treating bipolar depression.Your doctor will prescribe Effexor with caution if you have high blood pressure; heart, liver, or kidney disease; or a history of seizures or mania.

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Why Should Effexor Not Be Prescribed?

Anyone considering the use of Effexor or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Effexor has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Effexor and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly-especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior-and report them to the doctor immediately.

Warnings

Read the Medication Guide provided by your pharmacist before you start using venlafaxine and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication with food, usually 2 to 3 times daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment. The usual maximum dose for an adult is 375 milligrams each day.

Effexor Drug Interactions

Imipramine did not affect the pharmacokinetics of venlafaxine and ODV. The clinical significance of elevated 2-OH-desipramine levels is unknown. Metoprolol-Concomitant administration of venlafaxine (50 mg every 8 hours for 5 days) and metoprolol (100 mg every 24 hours for 5 days) to 18 healthy male subjects in a pharmacokinetic interaction study for both drugs resulted in an increase of plasma concentrations of metoprolol by approximately 30-40% without altering the plasma concentrations of its active metabolite, alpha?hydroxymetoprolol. Metoprolol did not alter the pharmacokinetic profile of venlafaxine or its active metabolite, O-desmethylvenlafaxine. Venlafaxine appeared to reduce the blood pressure lowering effect of metoprolol in this study.

Management Of Overdosage

In managing overdosage, consider the possibility of multiple drug involvement. The physician should consider contacting a poison control center for additional information on the treatment of any overdose. Treatment should consist of those general measures employed in the management of overdosage with any antidepressant. Ensure an adequate airway, oxygenation, and ventilation.

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