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Generic Effexor Xr Venlafaxine 37.5/75/150mg

Effexor XR is indicated for the treatment of Generalized Anxiety Disorder (GAD) as defined in DSM-IV. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. The efficacy of Effexor XR in the treatment of GAD was established in 8-week and 6-month placebo-controlled trials in adult outpatients diagnosed with GAD according to DSM-IV criteria Generalized Anxiety Disorder (DSM-IV) is characterized by excessive anxiety and worry (apprehensive expectation) that is persistent for at least 6 months and which the person finds difficult to control.

Package	Price	Per Pill	Order
37.5mg × 30 pills	$54.60	US $ 1.82
37.5mg × 60 pills	$67.20	US $ 1.12
37.5mg × 90 pills	$79.80	US $ 0.89
37.5mg × 120 pills	$92.40	US $ 0.77
37.5mg × 180 pills	$127.60	US $ 0.71
37.5mg × 360 pills	$243.20	US $ 0.68

Package	Price	Per Pill	Order
75mg × 30 pills	$67.20	US $ 2.24
75mg × 60 pills	$92.40	US $ 1.54
75mg × 90 pills	$117.60	US $ 1.31
75mg × 120 pills	$142.80	US $ 1.19
75mg × 180 pills	$193.20	US $ 1.07
75mg × 360 pills	$344.40	US $ 0.96

Package	Price	Per Pill	Order
150mg × 30 pills	$92.40	US $ 3.08
150mg × 60 pills	$142.80	US $ 2.38
150mg × 90 pills	$193.20	US $ 2.15
150mg × 120 pills	$0.00	US $ 0.00
150mg × 180 pills	$344.40	US $ 1.91

Why Should Effexor Not Be Prescribed?

In the clinical trials establishing the efficacy of Effexor XR in moderately depressed outpatients, the initial dose of venlafaxine was 75 mg/day. For some patients, it may be desirable to start at 37.5 mg/day for 4 to 7 days, to allow new patients to adjust to the medication before increasing to 75 mg/day. While the relationship between dose and antidepressant response for Effexor XR has not been adequately explored, patients not responding to the initial 75 mg/day dose may benefit from dose increases to a maximum of approximately 225 mg/day. Dose increases should be in increments of up to 75 mg/day, as needed, and should be made at intervals of not less than 4 days, since steady state plasma levels of venlafaxine and its major metabolites are achieved in most patients by day 4. In the clinical trials establishing efficacy, upward titration was permitted at intervals of 2 weeks or more; the average doses were about 140 to 180 mg/day It should be noted that, while the maximum recommended dose for moderately depressed outpatients is also 225 mg/day for Effexor (immediate release), more severely depressed inpatients in one study of the development program for that product responded to a mean dose of 350 mg/day (range of 150 to 375 mg/day).

Effexor Oral Storage

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Many people using this medication do not have serious side effects. Taking certain medications with this product could result in serious (rarely fatal) drug interactions. Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) with venlafaxine for 2 weeks before treatment, during treatment, and at least 7 days after your last dose of venlafaxine.

Effexor Xr Adverse Reactions

Patients treated with Effexor (immediate release) for at least 3 months in placebo-controlled 12-month extension trials had a mean final on-therapy increase in total cholesterol of 9.1 mg/dL compared with a decrease of 7.1 mg/dL among placebo-treated patients. Epidemiological studies of the case-control and cohort design that have demonstrated an association between use of psychotropic drugs that interfere with serotonin reuptake and the occurrence of upper gastrointestinal bleeding have also shown that concurrent use of an NSAID or aspirin may potentiate this risk of bleeding.

Effexor Xr Drug Interactions

Effexor XR treatment for up to 12 weeks in pooled premarketing Panic Disorder trials was associated with a mean final on-therapy increase in fasting serum triglyceride concentration of approximately 5.9 mg/dL, compared with a mean final increase of 0.9 mg/dL for placebo. Serotonin release by platelets plays an important role in hemostasis. Venlafaxine C max increased by 26% in EM subjects and 48% in PM subjects.