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Dosage adjustment is recommended when administering Famvir to patients with creatinine clearance values less than 60 mL/min. Any medication taken in excess can have serious consequences. Penciclovir was positive in the L5178Y mouse lymphoma assay for gene mutation/chromosomal aberrations, with and without metabolic activation (1000 mcg/mL). In human lymphocytes, penciclovir caused chromosomal aberrations in the absence of metabolic activation (250 mcg/mL).
OverdosageDo not take Famvir if you are sensitive to it or have ever had an allergic reaction to it. If Famvir is taken with certain other drugs, the effects of either could be increased, decreased, or altered. The effects of Famvir during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Famvir should be used during pregnancy only when the benefit to the mother clearly outweighs the potential risk to the baby. Famvir may appear in breast milk, and could affect a nursing infant. ADULTS Herpes Zoster The usual adult dose is 500 milligrams every 8 hours for 7 days. Recurrent Genital Herpes Treatment The usual dose is 125 milligrams twice a day for 5 days. Why Should Famvir Not Be Prescribed?Famvir speeds healing of shingles and genital herpes, but it is not a cure. Recurrent Genital Herpes Prevention The usual dose is 250 milligrams twice a day for up to one year. Famvir therapy to prevent genital herpes has not been tested for periods exceeding one year. Recurrent Oral or Genital Herpes in HIV-infected Individuals The usual dose is 500 milligrams twice a day for 7 days. Smaller doses are prescribed for people with damaged kidneys. This drug is used in certain patients to treat or help prevent outbreaks of herpes simplex on the skin (mouth, lips, genitals, anus). Famciclovir DosageFamciclovir is also used to treat outbreaks of shingles (herpes zoster). The viruses that cause these infections are similar. Dosage is based on your kidney function, medical condition, and response to therapy. This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same times each day. Do not take more or less of this drug than prescribed or stop taking it even for a short time unless directed to do so by your doctor. If overdose is suspected, contact your local poison control center or emergency room immediately. Famvir UsesIn that case, skip the missed dose and resume your usual dosing schedule. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (agitation, slowed thinking, confusion, hallucinations) sleepiness dizziness tiredness Tell your doctor immediately if any of these rare but very serious side effects occur: new fever chills cough breathing problems loss of appetite weight loss new diarrhea sore throat yellowing eyes/skin dark urine persistent nausea/vomiting severe tiredness easy bruising/bleeding A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. How To Use Famvir OralIf you miss a dose, take it as soon as you remember unless it is within 2 hours of your next dose. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Symptoms of a serious allergic reaction may include: rash itching/swelling (especially of the face/tongue/throat) severe dizziness trouble breathing This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. Famvir StorageDo not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Headache, nausea, vomiting, diarrhea, gas, stomach pain, tiredness, and tingling of hands/feet may occur as your body adjusts to the medication. Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. |
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