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Generic Hyzaar 50mg + 12.5

Replacement Therapy: The combination may be substituted for the titrated components. Dose Titration by Clinical Effect: A patient whose blood pressure is not adequately controlled with losartan monotherapy or hydrochlorothiazide alone, may be switched to Hyzaar 50-12.5 (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily. If blood pressure remains uncontrolled after about 3 weeks of therapy, the dose may be increased to two tablets of Hyzaar 50-12.5 once daily or one tablet of Hyzaar 100-25 (losartan 100 mg/hydrochlorothiazide 25 mg) once daily.

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Most Important Fact About Hyzaar

Hyzaar is indicated to treat hypertension or high blood pressure. instructions...Keep in a tightly closed container at room temperature. Obtain the exact dosage of Hyzaar from your doctor or physician. The dosage of Hyzaar may vary from person to person. The usual dosage of Hyzaar is one tablet a day. Hyzaar dosage may also be increased to two tablets a day if the patient does not respond effectively on the usual dosage of Hyzaar. In patients who are intravascularly volume-depleted (e.g., those treated with diuretics), symptomatic hypotension may occur after initiation of therapy with Hyzaar.

Hyzaar Intake Guidelines

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. If you have ever had an allergic reaction to losartan, hydrochlorothiazide, or sulfa drugs, you should not take this medication. Hyzaar is taken with certain other drugs, the effects of either could be increased, decreased, or altered. The usual starting dose is one 50-12.5 tablet per day. This drug is used to treat high blood pressure (hypertension). No patient discontinued due to increases or decreases in serum potassium. The mean decrease in serum potassium in patients treated with various doses of losartan and hydrochlorothiazide was 0.123 mEq/L.

Hyzaar Dosage

The maximum dosage of Hyzaar drug must be two tablets a day only. Hyzaar may be taken with or without food. If you have bronchial asthma or a history of allergies, you may be at greater risk for an allergic reaction to this medication.Excessive sweating, severe diarrhea or vomiting could deplete your body fluids and cause your blood pressure to drop too low. Avoid alcohol while taking this medication. Side effects of Hyzaar drug are not common and are unlikely to occur. However, tell your doctor immediately if you experience any of the following side effects. If your blood pressure does not respond to this dose, after about 3 weeks the doctor may increase the dose to two 50-12.5

Adverse Reactions

Significant lethality was observed in mice and rats after oral administration of 1000 mg/kg and 2000 mg/kg, respectively, about 44 and 170 times the maximum recommended human dose on a mg/m basis. Limited data are available in regard to overdosage in humans. There were 2 (0.6%) and 0 (0.0%) cases of hypotension reported in the group treated with Hyzaar and the group treated with losartan, respectively. The most likely manifestation of overdosage would be hypotension and tachycardia; bradycardia could occur from parasympathetic (vagal) stimulation.