cardiovascular / Generic Inderal La

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Generic Inderal La

Generic Inderal La

Propranolol 40mg

If this medication is not taken regularly, your condition may worsen. If you miss a dose... Take it as soon as you remember. If it is within 8 hours of your next scheduled dose, skip the one you missed and go back to your regular schedule. Inderal LA provides propranolol hydrochloride in a sustained-release capsule for administration once daily. If patients are switched from Inderal Tablets to Inderal LA Capsules, care should be taken to assure that the desired therapeutic effect is maintained. If you suffer from asthma or other bronchial conditions, coronary artery disease, or kidney or liver disease, this medication should be used with caution.

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Warnings

This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. In general, patients with bronchospastic lung disease should not receive beta-blockers. If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Beta-adrenergic receptor blockade can cause reduction of intraocular pressure. In patients with hypertension, use of propranolol has been associated with elevated levels of serum potassium, serum transaminases, and alkaline phosphatase.

Inderal La Precautions

See also Warning and Precautions sections. Dizziness, lightheadedness, or tiredness may occur as your body adjusts to the medication. Nausea/vomiting, stomach pain, vision changes, trouble sleeping, and unusual dreams may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. For immediate release formulations, fatigue, lethargy, and vivid dreams appear dose related.

Inderal La Drug Interactions

Caution should be exercised when patients receiving a beta-blocker are administered a calcium-channel-blocking drug with negative inotropic and/or chronotropic effects. When combined with beta-blockers, ACE inhibitors can cause hypotension, particularly in the setting of acute myocardial infarction. The antihypertensive effects of clonidine may be antagonized by beta-blockers. Prazosin has been associated with prolongation of first dose hypotension in the presence of beta?blockers. Patients on long-term therapy with propranolol may experience uncontrolled hypertension if administered epinephrine as a consequence of unopposed alpha-receptor stimulation.

Overdosage

Supportive Therapy: Hypotension and bradycardia have been reported following propranolol overdose and should be treated appropriately. Glucagon can exert potent inotropic and chronotropic effects and may be particularly useful for the treatment of hypotension or depressed myocardial function after a propranolol overdose. Glucagon should be administered as 50?150 mcg/kg intravenously followed by continuous drip of 1-5 mg/hour for positive chronotropic effect.

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