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You may develop a rash during the first 2 to 8 weeks of Lamictal therapy, particularly if you are also taking Depakene or Depakote. If this happens, notify your doctor immediately. Your doctor can schedule a gradual reduction in dosage. Lamictal Chewable Dispersible (CD) tablets may be swallowed whole, chewed, or dissloved in liquid. When chewing the tablets, drink a small amount of water or diluted fruit juice to aid in swallowing. There are suggestions, yet to be proven, that the risk of rash may also be increased by (1) coadministration of Lamictal with valproate, (2) exceeding the recommended initial dose of Lamictal, or (3) exceeding the recommended dose escalation for Lamictal.
Lamictal General InformationWhen dissolving the tablets, add them to a small amount of water or diluted fruit juice (about 1 teaspoonful), and wait 1 minute until the tablets are completely dissolved. Swirl the solution and drink immediately. Do not try to cut the dose by drinking only part of the solution. If you miss a dose... Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. If you have kidney or liver disease, or heart problems, Lamictal should be used with caution. Lamictal may cause vision problems. If any develop, notify your doctor immediately. Lamictal Adverse ReactionsTell your doctor if you have: other illnesses, heart problems, liver problems, kidney problems, allergies (especially drug allergies). Sunscreen and/or protective clothing is recommended to protect against a possible severe rash, triggered by sunlight. Use caution operating machinery or engaging in activities, requiring alertness. If Lamictal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Following a suspected overdose, hospitalization of the patient is advised. General supportive care is indicated, including frequent monitoring of vital signs and close observation of the patient. These rashes (e.g., Stevens-Johnson syndrome) are more common in children (less than 16 years old) than in adults. Possible Side EffectsDizziness, diplopia, ataxia, blurred vision, nausea, and vomiting were dose related. Dizziness, diplopia, ataxia, and blurred vision occurred more commonly in patients receiving carbamazepine with Lamictal than in patients receiving other AEDs with Lamictal. Clinical data suggest a higher incidence of rash, including serious rash, in patients receiving concomitant valproate than in patients not receiving valproate Approximately 11% of the 3,378 adult patients who received Lamictal as adjunctive therapy in premarketing clinical trials discontinued treatment because of an adverse experience. |
