thyroid / Generic Levoxyl

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Generic Levoxyl

Generic Levoxyl

Levothyroxine bp 25/50/100/200mg

This medicine can improve symptoms of thyroid deficiency such as slow speech, lack of energy, weight gain, hair loss, dry skin, and feeling cold. Side effects that you should report to your doctor or health care professional as soon as possible:difficulty breathing, wheezing, or shortness of breath , chest pain , excessive sweating or intolerance to heat , fast or irregular heartbeat , nervousness , skin rash or hives , swelling of ankles, feet, or legs , tremors .Side If you are receiving this medicine for an underactive thyroid, it may be several weeks before you notice an improvement. Check with your doctor or health care professional if your symptoms do not improve.It may be necessary for you to take this medicine for the rest of your life.

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Side Effects

effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):changes in appetite , changes in menstrual periods , diarrhea , hair loss , headache , trouble sleeping , weight loss.This In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Regardless of the indication for use, careful dosage titration is necessary to avoid the consequences of over- or under-treatment.

Precautions

In adult patients with primary (thyroidal) hypothyroidism, serum TSH levels (using a sensitive assay) alone may be used to monitor therapy. The frequency of TSH monitoring during levothyroxine dose titration depends on the clinical situation but it is generally recommended at 6 - 8 week intervals until normalization. The recommended frequency of monitoring of TSH and total or free T 4 in children is as follows: at 2 and 4 weeks after the initiation of treatment; every 1 - 2 months during the first year of life; every 2 - 3 months between 1 and 3 years of age; and every 3 to 12 months thereafter until growth is completed.

Levothyroxine Bp Adverse Reactions

Many drugs affect thyroid hormone pharmacokinetics and metabolism (e.g., absorption, synthesis, secretion, catabolism, protein binding, and target tissue response) and may alter the therapeutic response to Levoxyl. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and action of other drugs. These include urticaria, pruritus, skin rash, flushing, angioedema, various GI symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing.

Treatment Of Overdosage

Acute Massive Overdosage - This may be a life-threatening emergency, therefore, symptomatic and supportive therapy should be instituted immediately. If not contraindicated (e.g., by seizures, coma, or loss of the gag reflex), the stomach should be emptied by emesis or gastric lavage to decrease gastrointestinal absorption. Activated charcoal or cholestyramine may also be used to decrease absorption. Central and peripheral increased sympathetic activity may be treated by administering B-receptor antagonists, e.g., propranolol (1 to 3 mg intravenously over a 10-minute period, or orally, 80 to 160 mg/day). Provide respiratory support as needed; control congestive heart failure; control fever, hypoglycemia, and fluid loss as necessary.

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