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Generic Lioresal Baclofen 10mg

Baclofen belongs to two groups of medications known as muscle relaxants and antispastics. It is used to treat spasticity (uncontrolled muscle movements) caused by multiple sclerosis, spinal cord injuries, or spinal cord diseases. It is believed to work mainly by relaxing the muscles. The recommended adult dose of baclofen varies according to need but is usually started at doses of 5 mg three times a day for 3 days followed by 10 mg three times a day for 3 days and so on until the best dose is reached.

Package	Price	Per Pill	Order
10mg × 60 pills	$52.74	US $ 0.88
10mg × 90 pills	$72.78	US $ 0.81

How does Baclofen work?

Baclofen is thought to work by binding to receptors in the spinal cord called GABA-B receptors. The effect of this is to "damp down" the nerve signals that are carried in the spinal cord to the muscles. This reduces the contraction and tension in the muscles.

Adverse Reactions Related To Baclofen

In most cases reported, coma was reversible without sequelae after drug was discontinued. Symptoms of Lioresal INTRATHECAL overdose were reported in a sensitive adult patient after receiving a 25 mcg intrathecal bolus. Treatment Suggestions for Overdose: There is no specific antidote for treating overdoses of Lioresal INTRATHECAL (baclofen injection); however, the following steps should ordinarily be undertaken: Residual Lioresal INTRATHECAL solution should be removed from the pump as soon as possible. Patients with respiratory depression should be intubated if necessary, until the drug is eliminated.

How can Baclofen affect other medicines?

If baclofen is taken with alcohol or other medicines that cause drowsiness, increased drowsiness is likely. If baclofen is taken with tricyclic antidepressants, such as imipramine, severe muscular weakness may possibly occur. Baclofen can lower blood pressure, hence if it is taken by people taking blood pressure lowering medicines (antihypertensives) this effect is likely to be increased. If you are receiving medicines for high blood pressure your doctor may want to decrease your doses to avoid your blood pressure falling too low.