blood pressure / Generic Lopid

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Generic Lopid

Generic Lopid

Gemfibrozil 300mg

8, 9, 10, 11). Do not share this medication with others. Laboratory and/or medical tests (e.g., blood triglyceride and cholesterol levels, liver function tests, complete blood count, fasting blood sugar levels or FBS) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. ADULTS The recommended dose is 1,200 milligrams divided into 2 doses, given 30 minutes before the morning and evening meals. CHILDREN Safety and effectiveness of Lopid have not been established for use in children. Long-term studies have been conducted in mice at 0.1 and 0.7 times the human exposure (based on AUC). There were no statistically significant differences from controls in the incidence of liver tumors, but the doses tested were lower than those shown to be carcinogenic with other fibrates.

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Recommended Dosage For Lopid

The patients are recommended not to use other cholesterol lowering drugs while they are under treatment with Lopid, in order to avoid the development of severe muscle wasting. The drugs which are included in this category are: Atorvastatin (Lipitor), Fluvastatin (Lescol), Lovastatin (Mevacor), Pravastatin (Pravachol), Simvastatin (Zocor), and so on. Patients should also avoid taking Lopid along with blood thinning drugs such as Coumadin; if a therapy with a blood thinning remedy is crucial for the patient's health, its dose could be reduced in order to avoid an abnormal bleeding.

Lopid Drug Reactions

Long-term studies have been conducted in rats at 0.2 and 1.3 times the human exposure (based on AUC). The incidence of benign liver nodules and liver carcinomas was significantly increased in high dose male rats. The incidence of liver carcinomas increased also in low dose males, but this increase was not statistically significant (p=0.1). Male rats had a dose-related and statistically significant increase of benign Leydig cell tumors. The higher dose female rats had a significant increase in the combined incidence of benign and malignant liver neoplasms. Lopid should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lopid Adverse Reactions

Rarely, severe anemia, leukopenia, thrombocytopenia, and bone marrow hypoplasia have been reported. These are usually reversible when Lopid is discontinued. The risk of myopathy and rhabdomyolysis is increased with combined gemfibrozil and HMG-CoA reductase inhibitor therapy Myopathy or rhabdomyolysis with or without acute renal failure have been reported as early as three weeks after initiation of combined therapy or after several months (refs.

Lopid Drug Interactions

CAUTION SHOULD BE EXERCISED WHEN ANTI-COAGULANTS ARE GIVEN IN CONJUNCTION WITH Lopid. THE DOSAGE OF THE ANTICOAGULANT SHOULD BE REDUCED TO MAINTAIN THE PROTHROMBIN TIME AT THE DESIRED LEVEL TO PREVENT BLEEDING COMPLICATIONS. Symptoms reported with overdosage were abdominal cramps, abnormal liver function tests, diarrhea, increased CPK, joint and muscle pain, nausea and vomiting. There have been reported cases of overdosage with Lopid. In one case, a 7-year-old child recovered after ingesting up to 9 grams of Lopid.

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