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Generic Micronase Glyburide(glibenclamide) 1.25/2.5/5mg

There is no fixed dosage regimen for the management of diabetes mellitus with Micronase Tablets or any other hypoglycemic agent. In addition to the usual monitoring of urinary glucose, the patient's blood glucose must also be monitored periodically to determine the minimum effective dose for the patient; to detect primary failure, ie, inadequate lowering of blood glucose at the maximum recommended dose of medication; and to detect secondary failure, ie, loss of adequate blood glucose lowering response after an initial period of effectiveness. Glycosylated hemoglobin levels may also be of value in monitoring the patient's response to therapy.

Package	Price	Per Pill	Order
1.25mg × 30 pills	$22.00	US $ 0.73
1.25mg × 60 pills	$40.00	US $ 0.67
1.25mg × 90 pills	$55.00	US $ 0.61
1.25mg × 120 pills	$65.00	US $ 0.54
1.25mg × 180 pills	$85.00	US $ 0.47
1.25mg × 360 pills	$160.00	US $ 0.44

Package	Price	Per Pill	Order
2.5mg × 30 pills	$25.00	US $ 0.83
2.5mg × 60 pills	$45.00	US $ 0.75
2.5mg × 90 pills	$60.00	US $ 0.67
2.5mg × 120 pills	$75.00	US $ 0.62
2.5mg × 180 pills	$100.00	US $ 0.56
2.5mg × 360 pills	$185.00	US $ 0.51

Package	Price	Per Pill	Order
5mg × 30 pills	$30.00	US $ 1.00
5mg × 60 pills	$55.00	US $ 0.92
5mg × 90 pills	$75.00	US $ 0.83
5mg × 120 pills	$95.00	US $ 0.79
5mg × 180 pills	$130.00	US $ 0.72
5mg × 360 pills	$230.00	US $ 0.64

Micronase Indications

If you take this medicine once a day, take it with breakfast or the first main meal of the day. Take your medicine at the same time each day. Patients who take this medicine once a day are recommended to take it during one of the meals. At the beginning of the treatment the doctor will prescribe you a dose of 2.5 mg to 5 mg of Micronase taken daily. Patients should try as much as possible to take every dose of Micronase at its due time. The patient should be informed of the potential risks and advantages of Micronase and of alternative modes of therapy. All sulfonylureas are capable of producing severe hypoglycemia.

Micronase Missed Dose

If Micronase is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Maintenance therapy usually ranges from 1.25 to 20 milligrams daily. Glyburide is an anti-diabetic drug (sulfonylurea-type) used along with a proper diet and exercise program to control high blood sugar. Take this medication by mouth with breakfast or the first main meal, usually once daily; or use as directed by your doctor. Some patients, especially those taking higher doses, may be directed to take this drug twice a day. The dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it.

Precautions

Storage temperature ranges differ according to different manufacturers, so consult your pharmacist for more information. It is a good habit to carry glucose tablets or gel to treat low blood sugar. Allergic skin reactions, eg, pruritus, erythema, urticaria, and morbilliform or maculopapular eruptions occurred in 1.5% of treated patients during clinical trials. Cases of hyponatremia have been reported with glyburide and all other sulfonylureas, most often in patients who are on other medications or have medical conditions known to cause hyponatremia or increase release of antidiuretic hormone. Mild hypoglycemic symptoms, without loss of consciousness or neurological findings, should be treated aggressively with oral glucose and adjustments in drug dosage and/or meal patterns.

Adverse Reactions

Hepatic porphyria and disulfiram-like reactions have been reported with sulfonylureas; however, hepatic porphyria has not been reported with Micronase and disulfiram-like reactions have been reported very rarely. Close monitoring should continue until the physician is assured that the patient is out of danger. Severe hypoglycemic reactions with coma, seizure, or other neurological impairment occur infrequently, but constitute medical emergencies requiring immediate hospitalization. If hypoglycemic coma is diagnosed or suspected, the patient should be given a rapid intravenous injection of concentrated (50%) glucose solution.