gastrointestinal / Generic Protonix

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Generic Protonix

Generic Protonix

Pantoprazole 40mg

The active ingredient in Protonix(pantoprazole sodium), Delayed-Release Tablets is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl] sulfinyl]-1 H -benzimidazole sesquihydrate, a compound that inhibits gastric acid secretion. Its empirical formula is C 16 H 14 F 2 N 3 NaO 4 S x 1. Protonix(pantoprazole sodium), Delayed-Release Tablets are indicated for the short-term treatment (up to 8 weeks) in the healing and symptomatic relief of erosive esophagitis. For those patients who have not healed after 8 weeks of treatment, an additional 8 week course of Protonix may be considered.

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Protonix Adverse Reactions

In general, pantoprazole has been well tolerated in both short-term and long-term trials. In two U.S. controlled clinical trials involving Protonix 10-, 20-, or 40-mg doses for up to 8 weeks, there were no dose-related effects on the incidence of adverse events. Protonix is therefore recommended during pregnancy only if clearly needed. If you are pregnant or plan to become pregnant, inform your doctor immediately. There is a possibility that Protonix may appear in breast milk, causing serious side effects in the nursing infant.

Special Information If You Are Pregnant Or Breastfeeding

Although no harmful effects during pregnancy are known, there's no definite proof of safety either. In vivo studies also suggest that pantoprazole does not significantly affect the kinetics of other drugs (cisapride, theophylline, diazepam [and its active metabolite, desmethyldiazepam], phenytoin, warfarin, metoprolol, nifedipine, carbamazepine, midazolam, clarithromycin, naproxen, piroxicam and oral contraceptives [levonorgestrel/ethinyl estradiol]) metabolized by CYPs 2C19, 3A4, 2C9, 2D6 and 1A2. Therefore, it is expected that pantoprazole would not significantly affect the pharmacokinetics of other drugs metabolized by these isozymes.

Recommended Dosage For Protonix

Overproduction of Stomach Acid The usual starting dose is 40 milligrams twice a day. Any medication taken in excess can have serious consequences. Although little is known about Protonix overdose in humans, in animal studies it interferes with coordination and reduces activity. If Protonix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. The same dose is used to maintain healing. The doctor may increase the dose if necessary. This medication is known as a proton pump inhibitor (PPI). Continue to take this medication for the whole time prescribed by your doctor, even if you are feeling better.

Protonix Notes

Do not share this medication with others. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Store the Canadian product between 59-86 degrees F (15-30 degrees C) in the recommended packaging. Do not store in the bathroom. Call your doctor for medical advice about side effects. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: warfarin Some products need stomach acid so that the body can absorb them properly (such as ampicillin, iron supplements, calcium supplements, dasatinib, azole antifungals including ketoconazole).

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