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Generic Remeron Mirtazapine 15/30mg

Store at room temperature (77 degrees F or 25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. See also the Warning section. Reported adverse events were classified using a standard COSTART-based dictionary terminology. The prescriber should be aware that these figures cannot be used to predict the incidence of side effects in the course of usual medical practice where patient characteristics and other factors differ from those which prevailed in the clinical trials. The electrocardiograms for 338 patients who received Remeron (mirtazapine), Tablets and 261 patients who received placebo in 6-week, placebo-controlled trials were analyzed.

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Remeron Precautions

Psychiatric/medical checkups (and possibly laboratory tests) must be done periodically to monitor your progress and check for side effects. Approximately 16 percent of the 453 patients who received Remeron (mirtazapine), Tablets in US 6-week controlled clinical trials discontinued treatment due to an adverse experience, compared to 7 percent of the 361 placebo-treated patients in those studies. Prolongation in QTc greater than 500 msec was not observed among mirtazapine-treated patients; mean change in QTc was +1.6 msec for mirtazapine and - 3.1 msec for placebo.

Remeron Storage

Consult your doctor for more details. Clinical experience with Remeron in patients with concomitant systemic illness is limited. Accordingly, care is advisable in prescribing mirtazapine for patients with diseases or conditions that affect metabolism or hemodynamic responses. Remeron has not been systematically evaluated or used to any appreciable extent in patients with a recent history of myocardial infarction or other significant heart disease. Remeron was associated with significant orthostatic hypotension in early clinical pharmacology trials with normal volunteers.

Mirtazapine Adverse Reactions

Events of major clinical importance are also described in the WARNINGS and PRECAUTIONS sections. Body as a Whole: frequent: malaise, abdominal pain, abdominal syndrome acute; infrequent: chills, fever, face edema, ulcer, photosensitivity reaction, neck rigidity, neck pain, abdomen enlarged; rare: cellulitis, chest pain substernal. Cardiovascular System: frequent: hypertension, vasodilatation; infrequent: angina pectoris, myocardial infarction, bradycardia, ventricular extrasystoles, syncope, migraine, hypotension; rare: atrial arrhythmia, bigeminy, vascular headache, pulmonary embolus, cerebral ischemia, cardiomegaly, phlebitis, left heart failure.

Remeron Drug Interactions

The only drug overdose death reported while taking Remeron was in combination with amitriptyline and chlorprothixene in a non-US clinical study. Based on plasma levels, the Remeron dose taken was 30 - 45 mg, while plasma levels of amitriptyline and chlorprothixene were found to be at toxic levels. There is very limited experience with Remeron (mirtazapine), Tablets overdose. In premarketing clinical studies, there were eight reports of Remeron overdose alone or in combination with other pharmacological agents.