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Generic Sporanox Itraconazole 100mg

If you are sensitive to or have ever had an allergic reaction to Sporanox or similar antifungal drugs such as ketoconazole, you should not take this medication. Make sure that your doctor is aware of any drug reactions that you have experienced.Sporanox can have a negative effect on the heart. It should not be used for fungal nail infections in people with cardiac problems such as congestive heart failure.Serious heart problems, such as irregular heartbeats and even death, have occurred in people who have taken Sporanox at the same time as cisapride, levacetylmethadol, pimozide, or cholesterol-lowering drugs known as statins, such as simvastatin.

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Sporanox Dosage

Ask your personal health care specialist to prescribe you a proper dose of Sporanox (one that you should take in on a regular basis). Sporanox treatment is strongly discouraged if you have liver disease or have experienced liver toxicity from other drugs. If you miss one of your prescribed doses of Sporanox, you should take it as soon as you recall. However, if it is time for another scheduled dose, you ought to skip the one that you have missed. In life-threatening situations, a loading dose should be used whether given as oral capsules or intravenously.

Dosage And Administration

The recommended dose is 200 mg once daily (2 capsules). Any drug taken in excess can have dangerous consequences. IV Injection: the recommended intravenous dose is 200 mg b.i.d. for four consecutive doses, followed by 200 mg once daily thereafter. Each intravenous dose should be infused over 1 hour. The safety and efficacy of Sporanox Injection administered for greater than 14 days is not known. See complete prescribing information for Sporanox (itraconazole), Injection. Sporanox has been associated with rare cases of serious hepatotoxicity, including liver failure and death.

Warnings

Some of these cases had neither pre-existing liver disease nor a serious underlying medical condition, and some of these cases developed within the first week of treatment. If clinical signs or symptoms develop that are consistent with liver disease, treatment should be discontinued and liver function testing performed. The absorption of itraconazole may be decreased with the concomitant administration of antacids or gastric acid secretion suppressors. Instruct patients about the signs and symptoms of congestive heart failure, and if these signs or symptoms occur during Sporanox administration, they should discontinue Sporanox and contact their healthcare provider immediately. Instruct patients to stop Sporanox treatment immediately and contact their healthcare provider if any signs and symptoms suggestive of liver dysfunction develop.

Precautions

In patients with elevated or abnormal liver enzymes or active liver disease, or who have experienced liver toxicity with other drugs, treatment with Sporanox is strongly discouraged unless there is a serious or life threatening situation where the expected benefit exceeds the risk. Liver function monitoring should be done in patients with pre-existing hepatic function abnormalities or those who have experienced liver toxicity with other medications and should be considered in all patients receiving Sporanox. Treatment should be stopped immediately and liver function testing should be conducted in patients who develop signs and symptoms suggestive of liver dysfunction.