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You are allergic to any ingredient in Tetracycline or other tetracycline antibiotics (eg, doxycycline), you are currently taking acitretin or methoxyflurane. Take Tetracycline with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Tetracycline. Do not take antacids containing aluminum, calcium, or magnesium; preparations containing bismuth, iron, zinc, or sodium bicarbonate; or calcium rich foods (eg, milk, dairy products, calcium-enriched juices) within 2 to 3 hours before or after taking Tetracycline.
Before Using Tetracycline :Some medical conditions may interact with Tetracycline. Take Tetracycline on an empty stomach at least 1 hour before or 2 hours after a meal. Safety and effectiveness in this age group have not been confirmed. PREGNANCY and BREAST-FEEDING: Tetracycline has been shown to cause harm to the human fetus. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Tetracycline during pregnancy. Important Safety Information:If superinfection occurs, the antibiotic should be discontinued and appropriate therapy instituted. NOTE: Superinfection of the bowel by staphylococci may be life-threatening. Pseudotumor cerebri (benign intracranial hypertension) in adults has been associated with the use of tetracyclines. The usual clinical manifestations are headache and blurred vision. Bulging fontanels have been associated with the use of tetracyclines in infants. Tetracycline General PrecautionsAll patients with gonorrhea should have a serologic test for syphilis at the time of diagnosis. PENICILLIN - Since bacteriostatic drugs like tetracycline may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin. ANTICOAGULANTS - Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. OverdosageLong-term studies conducted in rats and mice to determine whether tetracycline hydrochloride has carcinogenic potential were negative. Some related antibiotics (oxytetracycline, minocycline) have shown evidence of oncogenic activity in rats. In two in vitro mammalian cell assay systems (L51784y mouse lymphoma and Chinese hamsterlung cells), there was evidence of mutagenicity at tetracycline hydrochloride concentrations of 60 and 10 ?g/mL, respectively. Tetracycline hydrochloride had no effect on fertility when administered in the diet to male and female rats at a daily intake of 25 times the human dose. Tetracyclines are present in the milk of lactating women who are taking a drug in this class. |
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