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Generic Trandate Labetalol 50/100/200mg

This medication is used to treat severe high blood pressure (hypertension). DOSAGE MUST BE INDIVIDUALIZED. The recommended initial dosage is 100 mg twice daily whether used alone or added to a diuretic regimen. After 2 or 3 days, using standing blood pressure as an indicator, dosage may be titrated in increments of 100 mg b.i.d. every 2 or 3 days. The usual maintenance dosage of labetalol HCl is between 200 and 400 mg twice daily. Since the full antihypertensive effect of labetalol HCl is usually seen within the first 1 to 3 hours of the initial dose or dose increment, the assurance of a lack of an exaggerated hypotensive response can be clinically established in the office setting.

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Dosage And Administration

The antihypertensive effects of continued dosing can be measured at subsequent visits, approximately 12 hours after a dose, to determine whether further titration is necessary. Store the vials at room temperature between 36 and 86 degrees F (2 to 30 degrees C) and away from light. Do not freeze. During controlled hypotensive anesthesia using labetalol HCl in association with halothane, high concentrations (3% or above) of halothane should not be used because the degree of hypotension will be increased and because of the possibility of a large reduction in cardiac output and an increase in central venous pressure.

Drug Class And Mechanism

Trandate blocks receptors of the adrenergic nervous system. When trandate attaches to and blocks the receptors, the arterial muscles relax, and the arteries expand, resulting in a fall in blood pressure. After dilution in the correct IV fluids, this product is stable for 24 hours refrigerated or at room temperature. If you have a history of severe allergic reactions, consult your doctor or pharmacist. Normal doses of epinephrine may not be as effective while you are using this medication. If you are diabetic, this drug may block certain symptoms of low blood sugar.

Trandate Missed Dose

Use caution when performing activities that require alertness such as driving or using machinery. Limit alcoholic beverages. Overdosage with labetalol HCl causes excessive hypotension that is posture sensitive and, sometimes, excessive bradycardia. Patients should be placed supine and their legs raised if necessary to improve the blood supply to the brain. If these effects become persistent or too bothersome, consult with your personal health care specialist. Normodyne has a list of interactions with other drugs.

Warnings

However, if you have reasons to suspect you are suffering from an overdose with this drug, you should immediately contact your doctor or go to the nearest hospital to seek emergency medical attention. Tell your doctor immediately if these unlikely but serious side effects occur: fainting, leg pain, increased sweating, increased urination, unusual thirst. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: unusually slow or irregular heartbeat, persistent loss of appetite, stomach pain, persistent sore throat or fever, easy bleeding or bruising, vision changes, difficulty urinating, mental/mood changes. Rare, but possibly fatal, liver problems have occurred during labetalol use.

Normodyne Missed Dose

If you happen to miss one dose of Normodyne, take it as soon as you remember, unless it is almost time for another intake. If it is almost time for another dose, skip the missed dose entirely and continue with your normal schedule. There is also a chance for very severe Normodyne side effects to occur. You should consult with your personal health care specialist and tell him about all other drugs you are currently taking, as some of them may affect or be affected by Normodyne. Some of them are: diuretics , heart medication , cimetidine, glutethimide, asthma drugs , diabetes drugs, other high blood pressure drugs, arbutamine, halothane anesthetic, tricyclic antidepressants.

Possible Side Effects

Fatigue, nausea, or tingling of the scalp/skin may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if this potentially serious side effect occurs: dizziness. You should immediately contact your doctor if you happen to experience unusually slow or irregular heart beat, fainting, persistent loss of appetite, stomach pain, persistent fever or sore throat, vision changes, difficulty urinating, easy bleeding or bruising, mood changes. Also there have been recorded cases of rare, but possibly fatal liver problems occurring during Normodyne treatment. Seek emergency medical attention if you develop such symptoms as dark urine or jaundice (yellowing of the skin or eyes). Ask your personal health care specialist for a full list of Normodyne drug interactions.