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Generic Trileptal

Generic Trileptal

Oxcarbazepine 150/300/600mg

Trileptal helps reduce the frequency of partial epileptic seizures, a form of epilepsy in which neural disturbances are limited to a specific region of the brain and the victim remains conscious throughout the attack. Trileptal is typically used in the treatment of patients suffering from epilepsy. As monotherapy or in combination with other drugs, it is recommended for adults suffering from partial seizures, while in the case of children of over 4 years of age it is used to treat seizures in monotherapy only. In the case of children of, or over 2 years of age, this drug may only be employed in combination with other medication for the treatment of epilepsy.

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Trileptal Clinical Results

Trileptal may have other therapeutic uses as well, which are not covered in this information guide. Prior to starting a treatment with Trileptal, you should inform your prescriber of any other medical conditions you are suffering from - in particular you should inform him or her if you are suffering from kidney disorders, hyponatremia or if you have had recent seizures. This drug may cause dizziness or drowsiness. It is best that you avoid or employ caution in operating machinery or driving.

Trileptal Dosage

Trileptal can lead to a loss of sodium from the blood, resulting in a serious medical condition which, left untreated, could lead to convulsions, coma, and death. Your doctor should carefully monitor your blood sodium levels during treatment with Trileptal. Alert the doctor immediately if you develop warning signs such as nausea, headache, sluggishness, confusion, loss of feeling, or an increase in the frequency or severity of seizures. Trileptal may cause increased skin sensitivity, fever, and rash. If you are experiencing any of these symptoms, talk to your doctor immediately.

Possible Food And Drug Interactions When Taking Trileptal

Alcohol can intensify the sedative effects of Trileptal. Avoid alcohol while taking this drug.If For a full list of drug interactions, it is best to consult a pharmacist or a specialized physician. Do not start taking this medication before informing your prescriber of any other drugs you are currently taking, and do not start taking any other medication without first consulting with your personal health care specialist. Trileptal may interfere with the action of birth control pills. Clinically significant hyponatremia (sodium less than 125 mmol/L) can develop during Trileptal (oxcarbazepine) use. In the 14 controlled epilepsy studies 2.5% of Trileptal-treated patients (38/1,524) had a sodium of less than 125 mmol/L at some point during treatment, compared to no such patients assigned placebo or active control (carbamazepine and phenobarbital for adjunctive and monotherapy substitution studies, and phenytoin and valproate for the monotherapy initiation studies).

Dosage And Administration

The concomitant antiepileptic drugs can be completely withdrawn over 3-6 weeks while Trileptal may be increased as clinically indicated by a maximum increment of 10 mg/kg/day at approximately weekly intervals to achieve the recommended daily dose. Patients should be observed closely during this transition phase. Patients not currently being treated with antiepileptic drugs may have monotherapy initiated with Trileptal. There is little information on Trileptal overdose. Clinically significant hyponatremia generally occurred during the first three months of treatment with Trileptal, although there were patients who first developed a serum sodium less than 125 mmol/L more than one year after initiation of therapy.

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