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Generic Vepesid Etoposide 50mg

Although, no reports of fatal effects of Vepesid on breast-feeding mothers have been found, still doctors are not willing to rule out the possibilities. It is thus, highly recommended to take this drug only after consultation with a physician during pregnancy or while nursing a baby. So far, this drug has not been seriously tested on children and older patients. Users of Vepesid may experience side effects like vomiting, sores within the mouth or on the lips, skin problems, stomach upset, and sudden hair loss, quite often.

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How Should I Use This Medicine?

Intake of Vepesid may cause serious allergic reactions. Breathing trouble, closed throat, swollen lips, tongue, or face are the most serious ones. Side effects like poor bone marrow function followed by serious blood problems featured in excessive weakness, sudden bleeding can also take a toll. Don't ignore side effects like unusual stools with blood, sudden rise in body temperature, infection, tissue or vein reaction etc., as these may have serious consequences. But to be on the safer side it is always better to consult a physician and be sure about what is the right dose for you. So far no serious cases of Vepesid overdose have been found. Periodic complete blood counts should be done during the course of VePesid treatment.

Carcinogenesis (See Warnings), Mutagenesis, Impairment Of Fertility

Etoposide has been shown to be mutagenic in Ames assay. Treatment of Swiss-Albino mice with 1.5 mg/kg I.P. of VePesid on day 7 of gestation increased the incidence of intrauterine death and fetal malformations as well as significantly decreased the average fetal body weight. Bone marrow recovery is usually complete by day 20, and no cumulative toxicity has been reported. Fever and infection have also been reported in patients with neutropenia. Nausea and vomiting can usually be controlled with standard antiemetic therapy. Anaphylactic-like reactions characterized by chills, fever, tachycardia, bronchospasm, dyspnea, and/or hypotension have been reported to occur in 0.7% to 2% of patients receiving intravenous VePesid and in less than 1% of the patients treated with the oral capsules.

Vepesid Adverse Reactions

These reactions have usually responded promptly to the cessation of the infusion and administration of pressor agents, corticosteroids, antihistamines, or volume expanders as appropriate; however, the reactions can be fatal. Hypertension and/or flushing have also been reported. Blood pressure usually normalizes within a few hours after cessation of the infusion. Anaphylactic-like reactions have occurred during the initial infusion of VePesid.