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Generic Videx Didanosine 100mg

However, it's often hard to tell a side effect from a symptom of the disease. If you think the drug is causing problems, keep taking it until you've checked with your doctor. Only your doctor can determine whether the drug is at fault and adjust your dosage accordingly.Side Videx has also been known to cause serious and even fatal liver damage. Signs of a liver problem include weakness, fatigue, stomach discomfort, dizziness, a cold feeling, and a sudden change in heartbeat.

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How Should You Take Videx?

Videx belongs to a class of drugs known as nucleoside analogs. Only your doctor can determine whether the drug is at fault and adjust your dosage accordingly. If you develop these symptoms, stop taking Videx and call your doctor immediately. Also be sure to tell the doctor if you've ever had a liver problem or tend to abuse alcohol; the doctor will watch you especially closely. Videx can also effect the nervous system, causing changes in your eyesight or a feeling of tingling, numbness, or pain in your hands or feet (known as peripheral neuropathy).

Videx Side Effects

Patients with renal impairment may be at greater risk for pancreatitis if treated without dose adjustment. The frequency of pancreatitis is dose related. Obesity and prolonged nucleoside exposure may be risk factors. CHILDREN The recommended dose for pediatric patients 2 weeks of age and older varies according to the child's weight. Peripheral neuropathy, manifested by numbness, tingling, or pain in the hands or feet, has been reported in patients receiving Videx therapy. Peripheral neuropathy has occurred more frequently in patients with advanced HIV disease, in patients with a history of neuropathy, or in patients being treated with neurotoxic drug therapy, including stavudine.

Warnings

The mechanism and long-term consequences of these events are currently unknown. It's important to remember that Videx will not prevent the spread of HIV through sexual relations or contact with infected blood. Videx can cause several serious side effects. Severe and even fatal pancreatitis (inflammation of the pancreas) is one possibility, especially if you've had the problem in the past, suffer from kidney disease, or drink alcoholic beverages. Drug Interactions: Ribavirin has been shown in vitro to increase intracellular triphosphate levels of didanosine, which could cause or worsen clinical toxicities Tables 3 and 4 summarize the effects on AUC and C MAX, with a 90% or 95% confidence interval (CI) when available, following coadministration of Videx (didanosine) with a variety of drugs.

Recommended Dosage For Videx

Retinal changes and optic neuritis have been reported in adult and pediatric patients. The higher your dosage, the greater your chance of side effects. Redistribution/accumulation of body fat including central obesity, dorsocervical fat enlargement (buffalo hump), peripheral wasting, facial wasting, breast enlargement, and "cushingoid appearance" have been observed in patients receiving antiretroviral therapy. Alcohol increases your risk of developing serious side effects such as pancreatitis. Severe or even fatal reactions may occur if Videx is combined with tenofovir (Viread) or ribavirin (Rebetol, Virazol).

Didanosine Precautions

If you need to take Videx while you're using either of these medications, your doctor will monitor you closely. If any of the symptoms for pancreatitis, lactic acidosis, or peripheral neuropathy occur (see "Special warnings about this medication"), contact the doctor immediately. If Videx is taken with certain other medications, the effect of either may be increased, decreased, or altered. A SERIOUS TOXICITY OF Videx (didanosine), IS PANCREATITIS, WHICH MAY BE FATAL OTHER IMPORTANT TOXICITIES INCLUDE LACTIC ACIDOSIS/SEVERE HEPATOMEGALY WITH STEATOSIS; RETINAL CHANGES AND OPTIC NEURITIS; AND PERIPHERAL NEUROPATHY When Videx is used in combination with other agents with similar toxicities, the incidence of these toxicities may be higher than when Videx is used alone.

What Side Effects May Occur?

Combining Videx with Zerit increases the risk. Videx EC Delayed-Release Capsules For adults weighing 132 pounds or more, the recommended dose is 400 milligrams once a day. If you weigh less than 132 pounds, the usual dose is 250 milligrams once a day. Check with your doctor immediately if you develop such signs of pancreatitis as stomach pain, nausea, or vomiting; you may have to stop treatment with Videx. The effects of Videx during pregnancy have not been adequately studied. If you have a kidney or liver problem, your dosage may be reduced.